L13I (p.Leu13Ile) variant of IFNGR2 (Interferon gamma receptor 2)
L13I (p.Leu13Ile) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
L13I (p.Leu13Ile) variant details
- p.Leu13Ile
- gnomAD 21-33403580-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.236
- REVEL 0.18
- MetaLR 0.49
- MetaSVM -0.60
- CADD 19.80
- PolyPhen-2 0.94
- SIFT 0.52
- Population evidence available
- Structural context available
- Literature evidence available