L12P (p.Leu12Pro) variant of IFNGR2 (Interferon gamma receptor 2)
L12P (p.Leu12Pro) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
L12P (p.Leu12Pro) variant details
- p.Leu12Pro
- gnomAD 21-33403578-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.36
- MetaLR 0.45
- MetaSVM -0.72
- CADD 23.60
- PolyPhen-2 0.83
- SIFT 0.19
- Population evidence available
- Structural context available
- Literature evidence available