L12M (p.Leu12Met) variant of IFNGR2 (Interferon gamma receptor 2)
L12M (p.Leu12Met) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
L12M (p.Leu12Met) variant details
- p.Leu12Met
- gnomAD 21-33403577-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.19
- MetaLR 0.22
- MetaSVM -0.91
- CADD 18.10
- PolyPhen-2 0.08
- SIFT 0.20
- Population evidence available
- Structural context available
- Literature evidence available