L11P (p.Leu11Pro) variant of IFNGR2 (Interferon gamma receptor 2)
L11P (p.Leu11Pro) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
L11P (p.Leu11Pro) variant details
- p.Leu11Pro
- gnomAD 21-33403575-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.282
- REVEL 0.30
- MetaLR 0.23
- MetaSVM -0.85
- CADD 22.90
- PolyPhen-2 0.54
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available