L10V (p.Leu10Val) variant of IFNGR2 (Interferon gamma receptor 2)
L10V (p.Leu10Val) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
L10V (p.Leu10Val) variant details
- p.Leu10Val
- gnomAD 21-33403571-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.207
- REVEL 0.05
- MetaLR 0.27
- MetaSVM -1.00
- CADD 13.50
- PolyPhen-2 0.03
- SIFT 0.51
- Population evidence available
- Structural context available
- Literature evidence available