L10M (p.Leu10Met) variant of IFNGR2 (Interferon gamma receptor 2)
L10M (p.Leu10Met) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
L10M (p.Leu10Met) variant details
- p.Leu10Met
- gnomAD 21-33403571-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.234
- REVEL 0.10
- MetaLR 0.29
- MetaSVM -0.84
- CADD 14.60
- PolyPhen-2 0.28
- SIFT 0.23
- Population evidence available
- Structural context available
- Literature evidence available