G14V (p.Gly14Val) variant of IFNGR2 (Interferon gamma receptor 2)
G14V (p.Gly14Val) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
G14V (p.Gly14Val) variant details
- p.Gly14Val
- TOPMed rs1441524595
- gnomAD rs1441524595
- Missense
- Variant Prioritization Score for Impact Estimate 0.315
- REVEL 0.29
- MetaLR 0.22
- MetaSVM -0.84
- CADD 16.40
- PolyPhen-2 0.33
- SIFT 0.58
- Most common in the Non-Finnish European population (allele frequency 3e-05)
- Structural context available