G14E (p.Gly14Glu) variant of IFNGR2 (Interferon gamma receptor 2)
G14E (p.Gly14Glu) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
G14E (p.Gly14Glu) variant details
- p.Gly14Glu
- gnomAD 21-33403584-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.289
- REVEL 0.24
- MetaLR 0.23
- MetaSVM -0.82
- CADD 15.60
- PolyPhen-2 0.33
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available
- Literature evidence available