G14A (p.Gly14Ala) variant of IFNGR2 (Interferon gamma receptor 2)
G14A (p.Gly14Ala) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
G14A (p.Gly14Ala) variant details
- p.Gly14Ala
- gnomAD 21-33403584-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.22
- MetaLR 0.17
- MetaSVM -0.91
- CADD 10.80
- PolyPhen-2 0.09
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available
- Literature evidence available