D25Y (p.Asp25Tyr) variant of IFNGR2 (Interferon gamma receptor 2)
D25Y (p.Asp25Tyr) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
D25Y (p.Asp25Tyr) variant details
- p.Asp25Tyr
- gnomAD 21-33403616-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.4
- REVEL 0.31
- MetaLR 0.48
- MetaSVM -0.17
- CADD 23.30
- PolyPhen-2 0.99
- SIFT 0.56
- Population evidence available
- Structural context available
- Literature evidence available