D25N (p.Asp25Asn) variant of IFNGR2 (Interferon gamma receptor 2)
D25N (p.Asp25Asn) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
D25N (p.Asp25Asn) variant details
- p.Asp25Asn
- TOPMed rs1475376636
- gnomAD rs1475376636
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.23
- MetaLR 0.42
- MetaSVM -0.43
- CADD 24.00
- PolyPhen-2 0.97
- SIFT 0.23
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available