D25H (p.Asp25His) variant of IFNGR2 (Interferon gamma receptor 2)
D25H (p.Asp25His) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
D25H (p.Asp25His) variant details
- p.Asp25His
- TOPMed rs1475376636
- gnomAD rs1475376636
- Missense
- Variant Prioritization Score for Impact Estimate 0.387
- REVEL 0.27
- MetaLR 0.48
- MetaSVM -0.19
- CADD 25.00
- PolyPhen-2 0.99
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 4.4e-05)
- Structural context available