A22T (p.Ala22Thr) variant of IFNGR2 (Interferon gamma receptor 2)
A22T (p.Ala22Thr) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
A22T (p.Ala22Thr) variant details
- p.Ala22Thr
- Ensembl rs2083656668
- Missense
- Variant Prioritization Score for Impact Estimate 0.139
- REVEL 0.15
- MetaLR 0.13
- MetaSVM -1.04
- CADD 0.28
- PolyPhen-2 0.00
- SIFT 0.62
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available