A22S (p.Ala22Ser) variant of IFNGR2 (Interferon gamma receptor 2)
A22S (p.Ala22Ser) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
A22S (p.Ala22Ser) variant details
- p.Ala22Ser
- gnomAD 21-33403607-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- REVEL 0.16
- MetaLR 0.09
- MetaSVM -1.01
- CADD 0.06
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the South Asian population (allele frequency 1.8e-05)
- Structural context available
- Literature evidence available