A22P (p.Ala22Pro) variant of IFNGR2 (Interferon gamma receptor 2)
A22P (p.Ala22Pro) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
A22P (p.Ala22Pro) variant details
- p.Ala22Pro
- gnomAD 21-33403607-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.147
- REVEL 0.17
- MetaLR 0.11
- MetaSVM -1.04
- CADD 0.46
- PolyPhen-2 0.00
- SIFT 0.69
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available
- Literature evidence available