A22D (p.Ala22Asp) variant of IFNGR2 (Interferon gamma receptor 2)
A22D (p.Ala22Asp) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
A22D (p.Ala22Asp) variant details
- p.Ala22Asp
- gnomAD 21-33403608-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.09
- MetaLR 0.15
- MetaSVM -1.03
- CADD 14.30
- PolyPhen-2 0.00
- SIFT 0.62
- Most common in the Non-Finnish European population (allele frequency 4e-06)
- Structural context available
- Literature evidence available