A21V (p.Ala21Val) variant of IFNGR2 (Interferon gamma receptor 2)
A21V (p.Ala21Val) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
A21V (p.Ala21Val) variant details
- p.Ala21Val
- gnomAD 21-33403605-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.276
- REVEL 0.03
- MetaLR 0.09
- MetaSVM -1.01
- CADD 14.60
- PolyPhen-2 0.00
- SIFT 0.56
- Population evidence available
- Structural context available
- Literature evidence available