A21T (p.Ala21Thr) variant of IFNGR2 (Interferon gamma receptor 2)
A21T (p.Ala21Thr) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
A21T (p.Ala21Thr) variant details
- p.Ala21Thr
- gnomAD 21-33403604-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.29
- REVEL 0.05
- MetaLR 0.08
- MetaSVM -1.04
- CADD 10.70
- PolyPhen-2 0.08
- SIFT 0.53
- Population evidence available
- Structural context available
- Literature evidence available