A21S (p.Ala21Ser) variant of IFNGR2 (Interferon gamma receptor 2)
A21S (p.Ala21Ser) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
A21S (p.Ala21Ser) variant details
- p.Ala21Ser
- gnomAD 21-33403604-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.294
- REVEL 0.05
- MetaLR 0.11
- MetaSVM -1.02
- CADD 11.40
- PolyPhen-2 0.23
- SIFT 0.45
- Population evidence available
- Structural context available
- Literature evidence available