A21G (p.Ala21Gly) variant of IFNGR2 (Interferon gamma receptor 2)
A21G (p.Ala21Gly) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
A21G (p.Ala21Gly) variant details
- p.Ala21Gly
- 1000Genomes rs1445046014
- TOPMed rs1445046014
- gnomAD rs1445046014
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- REVEL 0.06
- MetaLR 0.11
- MetaSVM -0.98
- CADD 8.99
- PolyPhen-2 0.30
- SIFT 0.33
- Most common in the 1KG:IBS population (allele frequency 0.0049)
- Structural context available