A20V (p.Ala20Val) variant of IFNGR2 (Interferon gamma receptor 2)
A20V (p.Ala20Val) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
A20V (p.Ala20Val) variant details
- p.Ala20Val
- TOPMed rs1406999141
- gnomAD rs1406999141
- Missense
- Variant Prioritization Score for Impact Estimate 0.31
- REVEL 0.06
- MetaLR 0.08
- MetaSVM -1.03
- CADD 15.40
- PolyPhen-2 0.14
- SIFT 0.22
- Most common in the African/African-American population (allele frequency 7.3e-05)
- Structural context available