A20P (p.Ala20Pro) variant of IFNGR2 (Interferon gamma receptor 2)
A20P (p.Ala20Pro) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
A20P (p.Ala20Pro) variant details
- p.Ala20Pro
- gnomAD 21-33403601-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.35
- REVEL 0.13
- MetaLR 0.11
- MetaSVM -1.03
- CADD 19.10
- PolyPhen-2 0.49
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available
- Literature evidence available