A19T (p.Ala19Thr) variant of IFNGR2 (Interferon gamma receptor 2)
A19T (p.Ala19Thr) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
A19T (p.Ala19Thr) variant details
- p.Ala19Thr
- TOPMed rs1253785897
- Missense
- Variant Prioritization Score for Impact Estimate 0.337
- REVEL 0.09
- MetaLR 0.25
- MetaSVM -0.88
- CADD 23.00
- PolyPhen-2 0.97
- SIFT 0.19
- Most common in the 1KG:PUR population (allele frequency 0.0052)
- Structural context available