A19S (p.Ala19Ser) variant of IFNGR2 (Interferon gamma receptor 2)
A19S (p.Ala19Ser) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
A19S (p.Ala19Ser) variant details
- p.Ala19Ser
- TOPMed rs1253785897
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- REVEL 0.10
- MetaLR 0.26
- MetaSVM -0.88
- CADD 22.60
- PolyPhen-2 0.98
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 2e-06)
- Structural context available