A19D (p.Ala19Asp) variant of IFNGR2 (Interferon gamma receptor 2)
A19D (p.Ala19Asp) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
A19D (p.Ala19Asp) variant details
- p.Ala19Asp
- gnomAD 21-33403599-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.425
- REVEL 0.21
- MetaLR 0.27
- MetaSVM -0.91
- CADD 22.60
- PolyPhen-2 0.99
- SIFT 0.18
- Population evidence available
- Structural context available
- Literature evidence available