A18S (p.Ala18Ser) variant of IFNGR2 (Interferon gamma receptor 2)
A18S (p.Ala18Ser) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
A18S (p.Ala18Ser) variant details
- p.Ala18Ser
- gnomAD 21-33403595-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.206
- REVEL 0.09
- MetaLR 0.16
- MetaSVM -0.88
- CADD 18.70
- PolyPhen-2 0.81
- SIFT 0.68
- Population evidence available
- Structural context available
- Literature evidence available