Y6H (p.Tyr6His) variant of IFNG (Interferon gamma)
Y6H (p.Tyr6His) in IFNG (Interferon gamma) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
Y6H (p.Tyr6His) variant details
- p.Tyr6His
- ExAC rs775727674
- gnomAD rs775727674
- Missense
- Variant Prioritization Score for Impact Estimate 0.227
- REVEL 0.12
- MetaLR 0.10
- MetaSVM -1.00
- CADD 16.90
- PolyPhen-2 0.46
- SIFT 0.18
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available