Y6D (p.Tyr6Asp) variant of IFNG (Interferon gamma)
Y6D (p.Tyr6Asp) in IFNG (Interferon gamma) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
Y6D (p.Tyr6Asp) variant details
- p.Tyr6Asp
- gnomAD 12-68159600-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.18
- MetaLR 0.09
- MetaSVM -0.99
- CADD 14.60
- PolyPhen-2 0.22
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available