Y6C (p.Tyr6Cys) variant of IFNG (Interferon gamma)
Y6C (p.Tyr6Cys) in IFNG (Interferon gamma) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
Y6C (p.Tyr6Cys) variant details
- p.Tyr6Cys
- gnomAD rs1377379698
- Missense
- Variant Prioritization Score for Impact Estimate 0.0755
- REVEL 0.04
- MetaLR 0.04
- MetaSVM -1.05
- CADD 1.08
- PolyPhen-2 0.00
- SIFT 0.25
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available