Y37C (p.Tyr37Cys) variant of IFNG (Interferon gamma)
Y37C (p.Tyr37Cys) in IFNG (Interferon gamma) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
Y37C (p.Tyr37Cys) variant details
- p.Tyr37Cys
- gnomAD rs1477303678
- Missense
- Variant Prioritization Score for Impact Estimate 0.541
- REVEL 0.52
- MetaLR 0.39
- MetaSVM -0.18
- CADD 26.40
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available