V45A (p.Val45Ala) variant of IFNG (Interferon gamma)
V45A (p.Val45Ala) in IFNG (Interferon gamma) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
V45A (p.Val45Ala) variant details
- p.Val45Ala
- gnomAD 12-68158240-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.30
- MetaLR 0.30
- MetaSVM -0.70
- CADD 16.10
- PolyPhen-2 0.86
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available