V28A (p.Val28Ala) variant of IFNG (Interferon gamma)
V28A (p.Val28Ala) in IFNG (Interferon gamma) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
V28A (p.Val28Ala) variant details
- p.Val28Ala
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.0616
- REVEL 0.00
- MetaLR 0.06
- MetaSVM -1.06
- CADD 0.94
- PolyPhen-2 0.03
- SIFT 0.45
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available