V15L (p.Val15Leu) variant of IFNG (Interferon gamma)
V15L (p.Val15Leu) in IFNG (Interferon gamma) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
V15L (p.Val15Leu) variant details
- p.Val15Leu
- ExAC rs757239347
- TOPMed rs757239347
- gnomAD rs757239347
- Missense
- Variant Prioritization Score for Impact Estimate 0.0674
- REVEL 0.01
- MetaLR 0.04
- MetaSVM -1.01
- CADD 3.39
- PolyPhen-2 0.00
- SIFT 0.22
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available