T4I (p.Thr4Ile) variant of IFNG (Interferon gamma)
T4I (p.Thr4Ile) in IFNG (Interferon gamma) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
T4I (p.Thr4Ile) variant details
- p.Thr4Ile
- ESP rs371849964
- ExAC rs371849964
- TOPMed rs371849964
- gnomAD rs371849964
- Missense
- Variant Prioritization Score for Impact Estimate 0.223
- REVEL 0.12
- MetaLR 0.21
- MetaSVM -0.85
- CADD 22.50
- PolyPhen-2 0.86
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available