S18F (p.Ser18Phe) variant of IFNG (Interferon gamma)
S18F (p.Ser18Phe) in IFNG (Interferon gamma) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
S18F (p.Ser18Phe) variant details
- p.Ser18Phe
- ExAC rs777144079
- TOPMed rs777144079
- gnomAD rs777144079
- Missense
- Variant Prioritization Score for Impact Estimate 0.136
- REVEL 0.02
- MetaLR 0.08
- MetaSVM -1.03
- CADD 2.86
- PolyPhen-2 0.05
- SIFT 0.78
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available