N48S (p.Asn48Ser) variant of IFNG (Interferon gamma)
N48S (p.Asn48Ser) in IFNG (Interferon gamma) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
N48S (p.Asn48Ser) variant details
- p.Asn48Ser
- NCI-TCGA Cosmic COSV5749
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.122
- REVEL 0.03
- MetaLR 0.05
- MetaSVM -1.04
- CADD 4.01
- PolyPhen-2 0.02
- SIFT 0.06
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available