N33K (p.Asn33Lys) variant of IFNG (Interferon gamma)
N33K (p.Asn33Lys) in IFNG (Interferon gamma) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
N33K (p.Asn33Lys) variant details
- p.Asn33Lys
- NCI-TCGA Cosmic COSV5749
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.0652
- REVEL 0.01
- MetaLR 0.04
- MetaSVM -1.03
- CADD 0.01
- PolyPhen-2 0.01
- SIFT 0.77
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available