L8S (p.Leu8Ser) variant of IFNG (Interferon gamma)
L8S (p.Leu8Ser) in IFNG (Interferon gamma) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
L8S (p.Leu8Ser) variant details
- p.Leu8Ser
- gnomAD 12-68159593-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.404
- REVEL 0.38
- MetaLR 0.31
- MetaSVM -0.73
- CADD 24.10
- PolyPhen-2 0.92
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available