L34I (p.Leu34Ile) variant of IFNG (Interferon gamma)
L34I (p.Leu34Ile) in IFNG (Interferon gamma) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
L34I (p.Leu34Ile) variant details
- p.Leu34Ile
- Ensembl rs2120750958
- Missense
- Variant Prioritization Score for Impact Estimate 0.305
- REVEL 0.25
- MetaLR 0.30
- MetaSVM -0.74
- CADD 21.50
- PolyPhen-2 0.80
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available