L12I (p.Leu12Ile) variant of IFNG (Interferon gamma)
L12I (p.Leu12Ile) in IFNG (Interferon gamma) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
L12I (p.Leu12Ile) variant details
- p.Leu12Ile
- gnomAD 12-68159582-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.16
- MetaLR 0.19
- MetaSVM -0.90
- CADD 22.40
- PolyPhen-2 0.72
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available