K35N (p.Lys35Asn) variant of IFNG (Interferon gamma)
K35N (p.Lys35Asn) in IFNG (Interferon gamma) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
K35N (p.Lys35Asn) variant details
- p.Lys35Asn
- NCI-TCGA Cosmic COSV9997
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.17
- MetaLR 0.24
- MetaSVM -0.85
- CADD 22.30
- PolyPhen-2 0.84
- SIFT 0.07
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available