K2T (p.Lys2Thr) variant of IFNG (Interferon gamma)
K2T (p.Lys2Thr) in IFNG (Interferon gamma) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
K2T (p.Lys2Thr) variant details
- p.Lys2Thr
- ExAC rs768834812
- TOPMed rs768834812
- gnomAD rs768834812
- Missense
- Variant Prioritization Score for Impact Estimate 0.105
- REVEL 0.02
- MetaLR 0.05
- MetaSVM -1.02
- CADD 6.90
- PolyPhen-2 0.06
- SIFT 0.13
- Most common in the South Asian population (allele frequency 0.00016)
- Structural context available