K2I (p.Lys2Ile) variant of IFNG (Interferon gamma)
K2I (p.Lys2Ile) in IFNG (Interferon gamma) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
K2I (p.Lys2Ile) variant details
- p.Lys2Ile
- gnomAD 12-68159611-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.135
- REVEL 0.03
- MetaLR 0.08
- MetaSVM -1.06
- CADD 15.00
- PolyPhen-2 0.36
- SIFT 0.01
- Most common in the South Asian population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available