I7T (p.Ile7Thr) variant of IFNG (Interferon gamma)
I7T (p.Ile7Thr) in IFNG (Interferon gamma) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
I7T (p.Ile7Thr) variant details
- p.Ile7Thr
- Ensembl rs1882655944
- Missense
- Variant Prioritization Score for Impact Estimate 0.182
- REVEL 0.09
- MetaLR 0.10
- MetaSVM -0.99
- CADD 20.50
- PolyPhen-2 0.04
- SIFT 0.04
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available