I14V (p.Ile14Val) variant of IFNG (Interferon gamma)
I14V (p.Ile14Val) in IFNG (Interferon gamma) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
I14V (p.Ile14Val) variant details
- p.Ile14Val
- ExAC rs745621454
- TOPMed rs745621454
- gnomAD rs745621454
- Missense
- Variant Prioritization Score for Impact Estimate 0.0584
- REVEL 0.00
- MetaLR 0.03
- MetaSVM -0.99
- CADD 0.02
- PolyPhen-2 0.00
- SIFT 0.74
- Most common in the South Asian population (allele frequency 9.4e-05)
- Structural context available