D44E (p.Asp44Glu) variant of IFNG (Interferon gamma)
D44E (p.Asp44Glu) in IFNG (Interferon gamma) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
D44E (p.Asp44Glu) variant details
- p.Asp44Glu
- gnomAD 12-68158242-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.395
- REVEL 0.18
- MetaLR 0.24
- MetaSVM -0.79
- CADD 16.70
- PolyPhen-2 0.50
- SIFT 0.05
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available