D25E (p.Asp25Glu) variant of IFNG (Interferon gamma)
D25E (p.Asp25Glu) in IFNG (Interferon gamma) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
D25E (p.Asp25Glu) variant details
- p.Asp25Glu
- gnomAD 12-68159541-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0835
- REVEL 0.05
- MetaLR 0.07
- MetaSVM -1.08
- CADD 0.09
- PolyPhen-2 0.00
- SIFT 0.52
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available