C23Y (p.Cys23Tyr) variant of IFNG (Interferon gamma)
C23Y (p.Cys23Tyr) in IFNG (Interferon gamma) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
C23Y (p.Cys23Tyr) variant details
- p.Cys23Tyr
- Ensembl rs2120751075
- Missense
- Variant Prioritization Score for Impact Estimate 0.309
- REVEL 0.24
- MetaLR 0.28
- MetaSVM -0.81
- CADD 20.70
- PolyPhen-2 0.85
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available