C23* (p.Cys23Ter) variant of IFNG (Interferon gamma)
C23* (p.Cys23Ter) in IFNG (Interferon gamma) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
C23* (p.Cys23Ter) variant details
- p.Cys23Ter
- rs1325493656
- NCI-TCGA Cosmic COSV9997
- gnomAD rs1325493656
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.349
- CADD 28.30
- UniProt: Variant assessed as somatic; high impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available