A46V (p.Ala46Val) variant of IFNG (Interferon gamma)
A46V (p.Ala46Val) in IFNG (Interferon gamma) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
A46V (p.Ala46Val) variant details
- p.Ala46Val
- ExAC rs772911580
- gnomAD rs772911580
- Missense
- Variant Prioritization Score for Impact Estimate 0.298
- REVEL 0.16
- MetaLR 0.19
- MetaSVM -0.91
- CADD 17.30
- PolyPhen-2 0.69
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available